Check for your Thyroid today
The thyroid gland is a butterfly-shaped organ located in the base of your neck. It releases hormones that control metabolism—the way your body uses energy. The thyroid is part of the endocrine system, which is made up of glands that produce, store, and release hormones into the bloodstream so the hormones can reach the body's cells. The thyroid gland uses iodine from the foods you eat to make two main hormones:
- Triiodothyronine (T3)
- Thyroxine (T4) (COPD)
It is important that T3 and T4 levels are neither too high nor too low. Two glands in the brain—the hypothalamus and the pituitary communicate to maintain T3 and T4 balance.
The hypothalamus produces TSH Releasing Hormone (TRH) that signals the pituitary to tell the thyroid gland to produce more or less of T3 and T4 by either increasing or decreasing the release of a hormone called thyroid stimulating hormone (TSH).
- When T3 and T4 levels are low in the blood, the pituitary gland releases more TSH to tell the thyroid gland to produce more thyroid hormones.
- If T3 and T4 levels are high, the pituitary gland releases less TSH to the thyroid gland to slow production of these hormones.
Recent research shows that low thyroid function is linked with greater type 2 diabetes risks. A recent study from Netherlands involving more than 8000 participants reveal that the risk for type 2 diabetes increased from 19% to 35% as thyroid stimulating hormone (TSH )rose from 0.4 to 4.0 mIU/L, while the diabetes risk dropped from 35% to 15% as free T4 increased from 11 to 25 pmol/L. The findings of the study was presented by Dr.Layal Chaker in the Annual Meeting of the Endocrine society ,ENDO 2016 and was presented the Outstanding Abstract Award.
Asked about what the mechanism for the association might be, Dr Chaker said that this isn't really known, but that thyroid hormone is important for energy expenditure and weight, so the effect might be mediated by BMI and other metabolic-syndrome components or perhaps a direct effect on beta-cell function.
While further research is warranted to add evidence in this area, considering the importance of the thyroid hormone and its multiple functions, ask your doctor if it has to be part of your routine master health check up .